Friday March 27th 2015

Mixing OxyContin with alcohol

Mixing OxyContin with alcohol

Are you considering mixing OxyContin with alcohol?

We’re going to look at the dangers and risks of mixing OxyContin with alcohol here. For example,  OxyContin overdose complications include slowed breathing and heart rate. You’ll learn What happens inside your body when these two drugs are combined and what side effects you can expect. Plus, what can go wrong? We invite you to ask questions about mixing OxyContin and alcohol in the comments, as well.

OxyContin and alcohol effects

OxyContin is a powerful prescription painkiller. Its main ingredient is oxycodone, an opiate. OxyContin can cause feelings of euphoria, especially when taken in amounts larger than prescribed. Some people mix Oxys with alcohol to intensify its pleasurable effects. In fact, alcohol has a chemical reaction with OxyContin in the body. But the two chemicals have an additive effect when combined. That means that the effects of the alcohol and OxyContin are both stronger when they’re mixed together, or even taken on the same day. This can cause accidental overdose.

In self-reports, people who have mixed OxyContin with alcohol experienced some of these effects:

  • drowsiness
  • euphoria
  • dream-like state
  • relaxation
  • numbness
  • wandering mind

Dangers of mixing OxyContin and alcohol

Taking alcohol and OxyContin together can result in serious adverse reactions; you can even die OxyContin. This is because of the additive effect they have on one another. Some potentially dangerous effects of mixing OxyContin with alcohol include:

  • dizziness
  • drowsiness
  • loss of consciousness
  • shallow breathing
  • impaired coordination
  • overdose
  • slowed heart rate

OxyContin is more dangerous when mixed with alcohol, but the reverse is also true. The alcohol’s sedative effects will be heightened when mixed with any narcotic. Drinking and using OxyContin can cause trouble concentrating and difficulty with coordination. You’re more likely to be involved in an accident or injure yourself, and you’ll also experienc emore intoxication from the alcohol. Not only that, but your alcohol tolerance will be lower than normal. This can lead to alcohol poisoning, so it’s important to be aware of the subjective signs of alcohol intoxication rather than count drinks.

OxyContin and alcohol overdose

It’s much easier to overdose on OxyContin when it’s taken with alcohol. OxyContin becomes stronger and more dangerous when combined with other depressants. In fact, doctors do not recommend mixing the two drugs at all. Sometimes it can be dangerous to take them on the same day, even hours apart, especially if you’re been prescribed an extended release version of OxyContin or chase snorting OxyContin effects.

OxyContin and alcohol deaths

Abusing OxyContin by taking more than a normal dose or by chewing, injecting or snorting OxyContin can cause overdose or even death. This risk increases when you add alcohol. Despite the dangers, OxyContin is often mixed with alcohol. But even normal doses of OxyContin combined with alcohol can cause your breathing to slow or stop completely. The only way to avoid these risks is to decide not to drink at all while on OxyContin.

Is it safe to drink on OxyContin?

No. It’s not safe to ever mix OxyContin and alcohol. The combination brings out the worst in both drugs. In fact, the FDA warns against mixing the two at all. You should ask your doctor for more information on how to stop drinking, if you find the idea of giving up drinking too difficult.

Mixing OxyContin alcohol questions

Do you still have questions about mixing OxyContin with alcohol or other substances? Please leave your OxyContin questions here. We try our best to answer all questions personally, and promptly. And if we don’t know the answer, we will refer you to someone who can help. Your experiences with mixing OxyContin and alcohol are also welcomed here.

Reference Sources: NIAAA pamphlet: Harmful Interactions, Mixing Alcohol with Medicines
Medline Plus: Oxycodone
PubMed: Oxycodone involvement in drug abuse deaths

FDA: Oxycodone hydrochloride oral solution medication guide

DailyMed: Oxycodone drug label

Photo credit: Montauk Beach

Leave a Reply

30 Responses to “Mixing OxyContin with alcohol
6:44 am November 8th, 2012

I took 2 oxycontins (the 3rd time I have ever taken them) yesterday, after a night of binge drinking and then yesterday drinking about 3/4 bottle of wine. I almost died. I was so close to death, I wrote an “I’m sorry” note to my family, I didn’t think I was going to pull through.

So today, not knowing anything about oxycontin (they weren’t mine) I looked up mixing the two. The first website I saw said death can occur. Don’t I know it.

I still feel like @&*T.

1:19 pm November 13th, 2012

Hi Ron. Thanks for sharing about your experience with OxyContin and alcohol. I do hope that others considering mixing the two will consider your real-life near-overdose and consider avoiding the combination.

3:58 am February 13th, 2013

I have been on Roxicodone for four years due to back pain after a failed fusion , I take about 65 mg in 24 hours. I am also a wine drinker, have been for many years. I am not a drug abuser and never take them more than prescribed. I routinely have about four glasses of wine in the evenings. Never had a problem. I have read what seems to say, that this amount of Roxicodone is not a large number if Opiod tolerant, which I certainly am since they are really not very effective anymore in pain control. In two months, Oxycontin goes generic, and I would much prefer that, but is it any more or less an issue with this level of alcohol than Roxicodone?
It seems not since it is time release??

9:01 am February 14th, 2013

Hello Joe. Well, I’d suggest that you take this question to a pharmacist who can better evaluate opioid tolerance and effects of alcohol. From what I’ve read, >2 drinks per day for men is an indication of problem drinking. And combined with an opioid, I wonder what affect this combination can have on your central nervous system and liver. Perhaps there is more going on there than you know at this time.

6:11 pm February 14th, 2013

Thanks, will ask her. So far my liver has always checked fine for years that’s why Roxi, no acetomenophen . I would prefer using medical marijuana as a supplement as it greatly reduces my pain, AND I am able to reduce and/ or, at least slow down the progressive increase in dosage caused by tolerance. Unfortunately our government has double crossed us on this , and now many doctors will not prescribe Opiods with MMJ because our DEA still wants to class it as an illegal street drug, and given the often present issue of urine tests, we are effectively blocked from this method that is approved by most agencies including the V.A. Now…..most unfortunate.

william shorey
6:17 pm February 14th, 2013

I have spinal stenosis.No pain while laying down.When I awake in the morning I take one Aleve tablet.At noon time would it be prohibative to have one can of lite beer before lunch and one oxicontin (50mg) after lunch?same routine at dinner time.I would not have anymore beer or oxicontin during a 24 hour period.I am 85 years old.

11:58 am February 15th, 2013

Hello William. Great question, and one that you can put to your prescribing doctor. To avoid having the interaction, you might try the beer first, make sure that you metabolize it (1-2 hours) and then take the Oxycontin. But for the second beer, you’d have to wait for at least 12 hours for the oxycodone to wear off (time controlled release). But check with your prescribing doctor. Slowed breathing and heart rate are nothing to mess around with, at any age!

Drew T
4:37 am March 2nd, 2013

I recently had a very close friend die as a result of what the toxicology reports and coroner decided was an accidental overdose of oxycodone in combination with alcohol. My friend was drinking and was dropped off at home and at some point took a pain pill and my friend for him the next morning dead on his couch. His levels were within prescription range and blood alcohol levels were over the legal limit, but nothing crazy. Just aBAD combo. Please, do NOT mix these two…it is often deadly. People don’t realize the risk involved…you get drunk, pop a pill and you pass out and lose ability to breathe or move in the case that you puke. Just so sad.

1:30 am March 4th, 2013

Thanks Drew, sorry about ur friend. My guess is he was not Opiod tolerant ( taking them on a regular schedule for five years like me)
Always sucks to lose a friend, for any reason. In my case, I am awake much of the night, I am never puke level intoxicated on anything. Those days are long gone thank God.

2:13 am March 8th, 2013

My boyfriend is a functional alcoholic and he is now taking Oxycodine…5/325mg…for severe back pain. He has taken about 30 pills in the last 8 days not to mention all the alcohol he drinks. Not sure what to do!!. He is dependent on the Oxycodine to help ease the pain but at the same time he is addicted to the alcohol and cant stop drinking while on the drug. Is the 5/325mg considered to be a large dosage? especially since he drinking at the same time.

6:12 am March 9th, 2013

Hi Sue. Perhaps the most effective help you can offer is to stop enabling the behavior and take actions to get yourself out of the relationship if he cannot stop. Otherwise, the effect of drinking and euphoria is just to compelling and he may already be hooked. You can also look into treatment for him, and/or consult with an addiction specialist for more information.

8:14 pm August 1st, 2013

Can oxyxodine give you more energy?

8:09 am August 13th, 2013

Hi Sue. Oxycodone is a central nervous system depressant. While many experience oxycodone as an energy-zapper, others, especially those prone to euphoric effect, can experience oxycodone as a mood and energy lift. But technically, oxycodone does not provide you with more energy. In fact, it slows down the central nervous system and body actions.

3:28 am September 11th, 2013

I routinely have a couple beers towards the end of the day, or a couple of mixed drinks at the house. I also take 20mg of oxycontin once every 12 hours for pain. I have broken bones that are healing from an accident. I have not had any issues drinking a couple drinks with the meds, but I do notice the feeling being slightly more than normal. I do not exceed the prescribed dosage, and do not drive or operate machinery. I am fully aware of the risks associated with mixing alcohol with oxycontin but I choose to anyway. If you do as well its at your own risk. Any doctor or medical professional will advise you not to mix the two and for a damn good reason.

5:30 pm September 13th, 2013

Robert I is obviously the job of the moderator to make sure we all know the professional opinion here. But then there is the
Street opinion, so we must mix the two with caution, just as the topic of this discussion. I recently went they a trial of MSContin to replace the Oxy, but it was a real problem. It did not help the pain nearly as well, but it did cause depression, profuse sweating and nodding off at the wheel ! So we switched back. I’m now on 30 mg Oxycontin every 8-10 hours and it is working well. The pain levels are more evened out, less up and down. I feel absolutely NOTHING from the Oxy as far as any feelings of euphoria or anything else, have not years. Good luck.

2:09 pm September 16th, 2013

Oops. As I read thru the threads I see I said I take 30mg per8 hours, typo…I only take 20mgs.
Which is roughly equal to the daily dose of Roxicodone previously. But the extended hours provided by Contin are a very welcome change.
The peaks and valleys of the Roxi were terrible.

12:29 pm September 23rd, 2013

I am utterly desperately hooked on oxycontin and take HUGE amounts.I want to stop but the pain i am in wont let me. I just cant stop myself from taking them even though i want to stop .I am compelled to have love to be able to stop or reduce to normal therapeutic levels and be able to have a glass of wine whilst on holiday which i dare not do at the moment.Crazy isnt it. Im afraid to have a glass of wine but dont mind risking my life taking overdoses doses of oxy , I cant tell my doctor or he will cut me off.

8:57 am September 24th, 2013

Hi Horace. IF you really want to stop, you’ll have to let go of the habit and be honest with your prescribing doctor. You’ll also need addiction treatment to address the psychological impulse for using. Once you can learn to control cravings, you don’t need to use anymore. Does this make sense?

4:57 pm September 24th, 2013

Horace, I don’t usually comment on these blogs because I never really thought other real people saw them on a current basis. But I want to tell you, I understand your crisis, it is a horrible feeling that we get when that WD starts, horrible. Nobody that has not been there will ever understand it. And I am very lucky that I have been able to control my intake over the past six years. I am at 60 mg per day and holding. I never feel any euphoria from it and thus don’t
“Miss or crave” that feeling. If you are not ready to go the professional route yet, try this…I found that when I am asleep, I can go longer periods between dosage, so start off trying to stretch your times with sleep. Even a little will show you how YOU can control it slowly. A little confidence will help. I don’t know what your taking per day. But it does sound like you have let it creep over where the limit should have been, and if you think you are beyond it, which obviously you do, you may have to tell the Doc. He won’t cut you off…remember, their oath is ” to do no harm” he will work with you to gradually control it. Look into something called Clonidine, I take that daily for sweats and to smooth out the W/D between doses and it works. Ask him about it. Sorry for the long message but I know when I’ve been in a bad slump over this whole thing I always wished I had someone who understood it and did not just look at me like some junkie on the street.

4:01 am September 26th, 2013

With low back pain, I am taking up to 75 mg of Oxycontin ER per day, though some days as little as 45 mg. I have not had any problem mixing that with 1.5 liters of red wine per day. I think the wine is preferable to increasing my Oxycontin intake. (I am trying to buy time, until Resiniferatoxin makes Oxycontin obsolete)

So, can anyone tell me how long it will take for my body to reach the maximum useful Oxycontin? And what happens then? Alternatives?

The real cure is Resiniferatoxin, but I fear Big Pharma/FDA will stall it forever, due to $.

3:53 pm September 26th, 2013

Interesting comment about Resiniferaroxin, my Doctor last week mentioned it. First I had heard of it will have to research. I’ve finally, after 6 years of surgeries, and trying various combinations of meds, found the best so far, with the least side effects, I’m now on 20 Mgs Oxycontin every 8 hours, and 4 Clonidine per day.
Occasionally when I have leg and hip spasms I take a Cyclobenzapren . I think the key thing for me has been adding the Clonidine. It really helped with the bad stuff that comes with it all.
I have a medical marijuana card and occasionally use a tiny amount to sleep, but not often. A couple of glasses of wine and I can start “trying” to rest and sleep. I do find that I don’t drink nearly as much as before all this stuff. But my Doc does not feel I’m in any danger whatsoever, being so Opiod tolerant. But I fully understand the dangers, especially someone doing all this as recreation, which I surely don’t understand.
1:02 am October 13th, 2013

My dearest friend is taking 80 mg of Opana (oxymorphone) twice a day for pain. We used to drink a half of a glass of red wine before dinner every night. She wants to do that again. Is that a bad idea?


7:43 am October 14th, 2013

Hello George. Thanks for your question. I’d suggest that you put this question to her prescribing doctor and/or pharmacist. Go with the expert medical opinion, as general health, age, weight, etc. all play a part in the advice that you’ll receive.

8:22 pm December 23rd, 2013

Hi there is 3 or 4 beers and 1 or 2 5 mg of oxycodone really dangerous, have been mixing with this combo for a few years now and just wondering if Im putting myself in real danger. Thank u

2:52 am January 29th, 2014

after taking your last dose of oxycontin 10 mgs ER ,when will it be safe to drink alcohol long should i wait fto drink again ?

2:57 am January 1st, 2015

My friend and I took two 80mg OxyContin and had a few drinks Tuesday night. I woke up to the ambulance trying to bring him back to life through CPR but he’s now dead and I’m lucky to be alife. I wish I had read up on it before and not now after its too late. His dad died of bowel cancer only 3 months ago so that’s how he got the tablets. We are always so cautious what we take but all it took was one moment of stupidness and now he’s gone. Please don’t anybody risk mixing these two things

3:42 pm January 14th, 2015

Hello Matthew. I’m very sorry for the terrible misfortune and for loosing a friend. Thank you for sharing your story. I hope it serves as a warning for others and prevents someone else from going down the same road. My thoughts and prayers are with you!

2:27 am March 3rd, 2015

I have insomnia/RLS- using zopitan and oxynorm. Can I use a small drink of whiskey to enhance the soporific effect of the zopitan? I am not in an abusive situation.

3:49 am March 5th, 2015

Is it possible to get a negative urine test for oxycodone and percocet if you drink a 12 pack a day? Under the care of pain mgmt doctor taking 80 MG extended release every 8 hrs..and fast acting 20 MG every 4-6 hrs for the last year & my Dr is trying to tell me that they don’t show up on my urine test! How can that be…I have been seeing this dr. For 7 yrs…and never tried to get a script early…my last MG increase was about a yr ago…and he cut me off trying to say it was not in my urine…but I take the meds!! How can this be??

4:09 am March 5th, 2015

I thought it was in ethical to cut someone off in this manner…now I am trying to find a new pain mgmt dr…I demanded that he give me a blood test..but he refused..then gave me a script for 7 days at 1/2 the dosage of extended release & no fast acting…no referrel…the urine test was done at an outside lab & my Ritalin &zoloft didn’t show up either.

Leave a Reply